Head-to-head for first-timers
Sesame vs Hers
Sesame and Hers both offer GLP-1 telehealth, but they make different trade-offs on how gentle the start is, honest pricing, real support and access. Here they are side-by-side on the Mama-Match Score — our first-timer rubric.
Sesame
Ranked #9 for first-timers · Grade B
Mama-Match
Best for: Confident, budget-first moms who are comfortable steering their own care.
Visit SesameHers
Higher scoreRanked #3 for first-timers · Grade B+
Mama-Match
Best for: Moms who want a familiar, women-first brand and the smoothest possible signup.
Visit HersThe verdict for a first step
Hers edges out Sesame on the Mama-Match Score, 87 to 83 (B+ vs B). Moms who want a familiar, women-first brand and the smoothest possible signup.
Sesame is still a genuine option — a cash-pay medical marketplace with some of the lowest posted GLP-1 prices anywhere — you're booking a clinician yourself, which is cheap and flexible but less hand-held. Weigh the six first-timer factors below against your own priorities.
Side-by-side on the six factors
Both providers scored on the same first-timer rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Sesame | Hers |
|---|---|---|
| Mama-Match Score | 83/100 · B | 87/100 · B+ |
| Overall rank | #9 | #3 |
| Semaglutide | $99/mo | $199/mo |
| Tirzepatide | $199/mo | Not disclosed |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Mama-Match
Sesame
Ranked #9 · Grade B
What we like
- Among the lowest posted cash prices for compounded semaglutide
- Transparent, upfront marketplace pricing — no membership to decode
- Nationwide, with flexible clinician booking on your schedule
The caveats
- You drive the process — less of a warm, guided first-timer experience
- Care can feel piecemeal since it's a marketplace, not one continuous program
Mama-Match
Hers
Ranked #3 · Grade B+
What we like
- Explicit women-focused brand many moms already recognize and trust
- Nationwide, with a very smooth app-driven signup and an oral/sublingual option
- Simple, mass-market onboarding that doesn't assume any background
The caveats
- Tirzepatide pricing isn't consistently posted up front
- Lighter on labs and metabolic detail behind the polished branding
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Mama-Match Score. Pricing, states and verification reflect each provider's public disclosures at last review; the Mama-Match Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Keep comparing Sesame and Hers against other providers we review for women.
- Sesame vs CoreAge Rx
- Sesame vs Eden
- Sesame vs Form Health
- Hers vs Noom Med
- Hers vs Trimi Health
- Hers vs Gala Health
Or browse the full comparison hub.