Head-to-head for first-timers
Trimi Health vs Sesame
Trimi Health and Sesame both offer GLP-1 telehealth, but they make different trade-offs on how gentle the start is, honest pricing, real support and access. Here they are side-by-side on the Mama-Match Score — our first-timer rubric.
Trimi Health
Higher scoreRanked #6 for first-timers · Grade B
Mama-Match
Best for: Budget-minded moms for whom the monthly number is the deciding factor, who are comfortable with compounded medicine and will check the prepay terms before signing.
Visit Trimi HealthSesame
Ranked #9 for first-timers · Grade B
Mama-Match
Best for: Confident, budget-first moms who are comfortable steering their own care.
Visit SesameThe verdict for a first step
Trimi Health edges out Sesame on the Mama-Match Score, 85 to 83 (B vs B). Budget-minded moms for whom the monthly number is the deciding factor, who are comfortable with compounded medicine and will check the prepay terms before signing.
Sesame is still a genuine option — a cash-pay medical marketplace with some of the lowest posted GLP-1 prices anywhere — you're booking a clinician yourself, which is cheap and flexible but less hand-held. Weigh the six first-timer factors below against your own priorities.
Side-by-side on the six factors
Both providers scored on the same first-timer rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Trimi Health | Sesame |
|---|---|---|
| Mama-Match Score | 85/100 · B | 83/100 · B |
| Overall rank | #6 | #9 |
| Semaglutide | $175/mo | $99/mo |
| Tirzepatide | $235/mo | $199/mo |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Mama-Match
Trimi Health
Ranked #6 · Grade B
What we like
- Some of the lowest flat, all-inclusive compounded pricing around, and it stays flat at every dose
- Both semaglutide and tirzepatide, in all 50 states
- A named clinical director and named compounding pharmacies, with a certificate of analysis if you ask
The caveats
- The headline $99/$125 rates require a full year prepaid — month-to-month is meaningfully higher
- Trustpilot rating is currently suppressed for a guidelines breach
- Compounded only, with no postpartum, breastfeeding, or PCOS-specific guidance
Mama-Match
Sesame
Ranked #9 · Grade B
What we like
- Among the lowest posted cash prices for compounded semaglutide
- Transparent, upfront marketplace pricing — no membership to decode
- Nationwide, with flexible clinician booking on your schedule
The caveats
- You drive the process — less of a warm, guided first-timer experience
- Care can feel piecemeal since it's a marketplace, not one continuous program
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Mama-Match Score. Pricing, states and verification reflect each provider's public disclosures at last review; the Mama-Match Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Keep comparing Trimi Health and Sesame against other providers we review for women.
- Trimi Health vs CoreAge Rx
- Trimi Health vs Eden
- Trimi Health vs Hers
- Sesame vs Form Health
- Sesame vs Noom Med
- Sesame vs Gala Health
Or browse the full comparison hub.