He and She MD review

He and She MD for moms: our verdict

$199/mo semaglutide, $299/mo tirzepatide month-to-month, dropping to $99 and $159 only on a full year prepaid. It names its pharmacies, its clinical group and its CMO. The advertised starting price is $139, but the regular rate settles nearer $199/mo — so read the headline as an intro offer, not as the monthly cost.

We looked at He and She MD the way moms actually have to: not just the monthly cost, but the right timing around pregnancy and nursing and honest, clear pricing from the start — the parts a generic weight-loss review skips.

What He and She MD actually costs

• Compounded semaglutide — Injectable, month-to-month: $199/mo
• Compounded semaglutide — Injectable, 3-month plan: $149/mo
• Compounded semaglutide — Injectable, 6-month plan: $139 to start, then $199/mo
• Compounded semaglutide — Injectable, 12-month plan: $99/mo
• Oral semaglutide — Oral, 12-month plan: $209/mo
• Brand-name semaglutide — Ozempic®, 12-month plan: $1299/mo

That's roughly in line with our list's median of ~$179/mo.

He and She MD prices flat across doses, so it doesn't climb as your dose does — which matters, because most women spend months titrating up.

That price covers the consult, the medication and shipping. It does not cover labs — that's billed separately.

The medications He and She MD prescribes

He and She MD lists semaglutide and tirzepatide. Offering both gives a prescribing clinician options, but PCOS or a history of gestational diabetes alone does not establish which medication is right for you. It can point you toward FDA-approved brand-name medications as well as the compounded versions — approved products carry the manufacturer's own pregnancy and breastfeeding label, which is cleaner to hand to an OB-GYN.

If you prefer an option without needles, check the exact product offered. FDA-approved oral semaglutide tablets have their own clinical trials and prescribing labels. Compounded oral or sublingual products are different: they are not FDA-approved and cannot be assumed equivalent to an approved tablet or injection. Ask the clinician about the formulation, evidence and instructions.

Where it operates. He and She MD lists its coverage as: 49 states — everywhere except Louisiana.

Where He and She MD fits — and where it doesn't — for moms

A good fit if…

• you want a real clinician who reads your history with the right timing around pregnancy and nursing in mind, not a questionnaire that approves you automatically.
• you want to discuss both semaglutide and tirzepatide with your prescribing clinician.

Look elsewhere if…

• you want friction-free cancellation — the fine print here is where the complaints cluster.

Trust, safety and oversight

Before choosing He and She MD, confirm the dispensing pharmacy and the clinician responsible for your prescription. Public information alone does not establish the quality of care you will receive. As with any compounded GLP-1, the most useful thing moms can do is confirm which licensed pharmacy fills the prescription and what's in the formula — we explain how we score oversight in our scoring methodology.

Pregnancy and breastfeeding need separate discussions with your clinician. GLP-1 weight-loss treatment is not recommended during pregnancy. During breastfeeding, the exact drug and formulation matter: Wegovy tablets are not recommended because of the SNAC absorption ingredient. Injectable semaglutide and tirzepatide labels call for weighing benefits, risks and the limits of infant-safety data; they do not establish that treatment is safe for every nursing parent. Compounded products do not inherit FDA approval from the branded drug. Discuss your own medication and timing before starting or changing treatment.

The bottom line

He and She MD is a reasonable option — weigh it on the right timing around pregnancy and nursing and honest, clear pricing from the start against the alternatives below. For moms comparing another compounded offer, CoreAge Rx describes prices and terms to confirm for the selected dose and plan.