Mama-Match
He and She MD review
A broad compounded-plus-brand menu with seven real price points — $199/mo standard semaglutide down to $99/mo on the 12-month plan — though nearly every itemized figure is the annual-prepay rate, and tirzepatide's standard monthly cost isn't published.
- HSA / FSA eligible
- Independently scored
- No insurance needed
Referral link, separate from the score
Every medical claim is cited to its primary source — the clinical trial or the FDA label — so you can open it and check it yourself. No one on this team is your healthcare professional. What follows is friendly information, never medical advice.
Gentler first steps than He and She MD
Providers we'd send a friend to, with the ones we work with listed first — CoreAge Rx leads our ranking on the score. Some of these links earn MamaGLP a referral commission.
- Meet CoreAge RxCoreAge RxOur #1 pick
The gentlest place to land if you're just starting out: one flat monthly price with no surprises, both medications in a single account, and an intake that walks you through it step by step instead of cornering you with a quiz.
- Meet Telos Rx
Four flat, posted price points and a written promise your cost won't climb with your dose — a real step up in clarity from what we found last check — undercut by a state list it still won't publish.
- Meet Found Health
The most complete option on the list: flat pricing that doesn't climb with your dose, the same cost for semaglutide and tirzepatide, insurance accepted in 49 states, and real access to brand-name GLP-1s — in exchange for a separate membership fee and rigid refund rules.
He and She MD at a glance
- Semaglutide
- $199/mo standard (injectable), $99/mo on the 12-month plan
- Tirzepatide
- $159/mo on the 12-month plan; standard monthly rate not itemized on the page checked
- Coverage
- All 50 states
- Brand-name
- Yes
How we scored He and She MD
Each factor is judged from He and She MD's actual pricing, disclosures and support, then combined into the Mama-Match Score of 59/100 using the same weighted six-factor framework we apply to every provider — never influenced by whether a provider pays us.
The start feels transactional — more cash register than welcome.
The cost is unpredictable, hidden behind a quiz, or in the premium range.
Little public detail about who oversees your care, and how.
Wide coverage, though not confirmed in every state.
Support is thin once the prescription ships.
Cancelling carries real friction — commitments, notice windows or non-refundable charges.
How we verified this review
- Last reviewed
- August 2026
- Confidence
- Medium
- Primary source
- heandshemd.com
Sourced from WLR's provider directory, independently re-verified live on heandshemd.com (2026-08-02). Seven price points confirmed on the weight-loss page, each explicitly marked as a 12-month-supply rate. The homepage banner separately references '$199/month' for injectable semaglutide as the 'from' price before the 12-month discount — treated as the standard month-to-month rate here. No equivalent standard-rate reference was found for tirzepatide.
What to expect when you sign up
We walked He and She MD's public signup (August 2026) — a first-hand look at the process. We did not create accounts, enter medical information, or complete checkout, so this is what any visitor sees, not a patient's outcome.
- 1The homepage lists seven real price points across compounded, oral, and brand forms of both molecules, all marked as 12-month-plan rates, no intake required to see the numbers
- 2A 5-minute quiz determines eligibility; a licensed U.S. clinician reviews before anything is prescribed
- 3The site states 'no hidden fees, ever' and free expedited shipping on every order
What we noticed
- A genuinely broad menu — compounded injectable, compounded oral, and FDA-approved brand (Ozempic, Zepbound) for both molecules, all priced — but every itemized figure is explicitly the 12-month-prepay rate, and only semaglutide's standard month-to-month rate ($199) is referenced, in the banner rather than the pricing table itself
- Tirzepatide's standard (non-annual-prepay) monthly rate was not found on the pages checked
- No named compounding pharmacy or medical director found on the pages checked, and no statement on video-visit requirements
Pricing
Prices re-verified
| Medication | Monthly | Plan |
|---|---|---|
| Compounded semaglutide | $199 | Injectable, standard monthlyReferenced in the homepage banner as the 'from' price before the 12-month-plan discount. |
| Compounded semaglutide | $99 | Injectable, 12-month planListed as '$99/month*' — the asterisk notes this is the price for a 12-month supply purchase. |
| Oral semaglutide | $209 | Oral, 12-month plan12-month prepaid rate; standard monthly rate not itemized on the page checked. |
| Brand semaglutide | $1299 | Ozempic®, 12-month plan12-month prepaid rate. |
| Compounded tirzepatide | $159 | Injectable, 12-month plan12-month prepaid rate; standard monthly rate not itemized on the page checked. |
| Oral tirzepatide | $269 | Oral, 12-month plan12-month prepaid rate. |
| Brand tirzepatide | $1399 | Zepbound®, 12-month plan12-month prepaid rate. |
Swipe the table to see plan details →
HSA/FSA is usually accepted for GLP-1 telehealth — check your plan. Prices reflect what He and She MD disclosed publicly at our last review and change often; confirm the current number on He and She MD's site.
What we like
- A genuinely broad menu — compounded injectable, compounded oral, and FDA-approved brand (Ozempic, Zepbound) for both molecules, all on one platform
- Seven real price points visible directly on the site, no intake required to see them
- States 'no hidden fees, ever' and free expedited shipping on every order
- A 5-minute quiz with licensed clinician review, described as a fast intake path
The caveats
- Nearly every itemized price is the 12-month-prepay rate — the standard month-to-month cost is only referenced for semaglutide ($199/mo), not tirzepatide
- No named compounding pharmacy or medical director found on the site
- No published time-to-first-dose or statement on whether a video visit is required
- Brand pricing ($1,299-$1,399/mo) is a steep jump from the compounded tiers — confirm which you're selecting before checkout
He and She MD for moms: our verdict
A broad compounded-plus-brand menu with seven real price points — $199/mo standard semaglutide down to $99/mo on the 12-month plan — though nearly every itemized figure is the annual-prepay rate, and tirzepatide's standard monthly cost isn't published. It runs about $99/mo, flat across every dose — toward the affordable end of what we track.
We looked at He and She MD the way moms actually have to: not just the monthly cost, but the right timing around pregnancy and nursing and honest, clear pricing from the start — the parts a generic weight-loss review skips.
What He and She MD actually costs
- Compounded semaglutide — Injectable, standard monthly: $199/mo
- Compounded semaglutide — Injectable, 12-month plan: $99/mo
- Oral semaglutide — Oral, 12-month plan: $209/mo
- Brand-name semaglutide — Ozempic®, 12-month plan: $1299/mo
- Compounded tirzepatide — Injectable, 12-month plan: $159/mo
- Oral tirzepatide — Oral, 12-month plan: $269/mo
That lands below the median ongoing price of about $149 across the providers we track for moms — a real cost advantage.
The medications He and She MD prescribes
He and She MD prescribes semaglutide and tirzepatide — the two molecules with the strongest published weight-loss results, and having both on one account matters when insulin resistance (common with PCOS and after gestational diabetes) makes tirzepatide the better fit. It can point you toward FDA-approved brand-name pens as well as the compounded versions — approved products carry the manufacturer's own pregnancy and breastfeeding label, which is cleaner to hand to an OB-GYN.
There's a needle-free oral or sublingual option on the menu, which appeals to moms who have been putting off injections — just set your expectations: oral and buccal delivery of these peptides is far less studied than the injectable versions used in the trials.
Where He and She MD fits — and where it doesn't — for moms
A good fit if…
- you want a real clinician who reads your history with the right timing around pregnancy and nursing in mind, not a questionnaire that approves you automatically.
- the monthly cost is a real barrier and you want a low, predictable number.
- you may need to switch between semaglutide and tirzepatide as your body and your hormones change.
- uninterrupted nationwide access matters to you — a move for the family shouldn't interrupt your care.
Look elsewhere if…
- you'd rather have a clinician talk the timing through with you, with the right timing around pregnancy and nursing in mind — that's what our #1 pick, CoreAge Rx, is built for.
Trust, safety and oversight
Our confidence is moderate — the core data holds up, but some details (state availability, program mechanics) aren't fully public. As with any compounded GLP-1, the most useful thing moms can do is confirm which licensed pharmacy fills the prescription and what's in the formula — we explain how we score oversight in our scoring methodology.
A standing caution for moms: GLP-1 medications are not proven safe during pregnancy or breastfeeding, and every label advises against use. None of this changes that — plan the timing with your own healthcare provider.
The bottom line
He and She MD is a genuine bargain for the price — weigh it on the right timing around pregnancy and nursing and honest, clear pricing from the start against the alternatives below. For most moms, CoreAge Rx is still the best choice overall — see why it tops our ranking.
The bottom line
Best for: Moms comfortable committing to a 12-month prepaid plan to reach the lowest advertised prices, and who want brand-name options on the same platform.
Keep comparing He and She MD
Head-to-heads and alternatives
Ranked boards
- Best GLP-1 for moms — a gentle first step
- Best GLP-1 for women — PCOS, cycles, perimenopause
- Best GLP-1 for first-timers (easiest to start)
- Most affordable GLP-1 with honest, clear pricing
- Best semaglutide for mothers — price and practicality
- Best semaglutide for women — compounded vs brand
- Best semaglutide for young moms — postpartum and budget
- Best tirzepatide for mothers — is it worth the extra
- Best tirzepatide for women — PCOS and insulin resistance
- Best GLP-1 with bilingual / Spanish-language support
He and She MD, answered
- How much does He and She MD cost?
- As of our last review, He and She MD's compounded pricing starts around $99/mo ($199/mo standard (injectable), $99/mo on the 12-month plan semaglutide, $159/mo on the 12-month plan; standard monthly rate not itemized on the page checked tirzepatide). Confirm the current all-in price on He and She MD's site before you commit.
- Is He and She MD safe to use while breastfeeding?
- Here is the honest answer: no GLP-1 — compounded or brand-name — is established as safe during pregnancy or breastfeeding, and the labels advise against use; He and She MD is no exception. Plan any GLP-1 for after weaning, and talk the timing through with your own clinician.
- Does He and She MD offer both semaglutide and tirzepatide?
- Yes — He and She MD offers both. Tirzepatide's dual action is often preferred when insulin resistance is driving the weight, which matters with PCOS and after gestational diabetes.
- Where does He and She MD land in your ranking?
- He and She MD scores 59/100 on our Mama-Match Score (rank #38), which weights six things that matter to a first-timer. Our #1 pick, CoreAge Rx, leads the ranking — see how they compare.
Prices, states and verification reflect what He and She MD disclosed publicly at our last review; the Mama-Match Score is our editorial judgment under the published methodology. This is gentle background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See our medical disclaimer and how we're funded.