Mama-Match
He and She MD review
$199/mo semaglutide, $299/mo tirzepatide month-to-month, dropping to $99 and $159 only on a full year prepaid. It names its pharmacies, its clinical group and its CMO.
- HSA / FSA eligible
- Independently scored
- No insurance needed
Referral link, separate from the score
Every medical claim is cited to its primary source — the clinical trial or the FDA label — so you can open it and check it yourself. No one on this team is your healthcare professional. What follows is friendly information, never medical advice.
He and She MD at a glance
- Semaglutide
- $199/mo month-to-month, $99/mo on the 12-month plan
- Tirzepatide
- $299/mo month-to-month, $159/mo on the 12-month plan
- Coverage
- 49 states — everywhere except Louisiana
- Brand-name
- Yes
How we scored He and She MD
Each factor is judged from He and She MD's actual pricing, disclosures and support, then combined into the Mama-Match Score of 60/100 using the same weighted six-factor framework we apply to every provider — never influenced by whether a provider pays us.
The start feels transactional — more cash register than welcome.
The cost is unpredictable, hidden behind a quiz, or in the premium range.
Little public detail about who oversees your care, and how.
Wide coverage, though not confirmed in every state.
Support is thin once the prescription ships.
Canceling carries real friction — commitments, notice windows or non-refundable charges.
How we verified this review
- Last reviewed
- August 2026
- Confidence
- High
- Primary source
- www.heandshemd.com/weight-loss/plans
$199 and $299 month to month, published plainly on the plans page. The $99 and $159 headlines require twelve months up front — $1,188 and $1,908 in a single charge — and every prepaid term reconciles arithmetically. Every state but Louisiana.
What to expect when you sign up
We walked He and She MD's public signup (August 2026) — a first-hand look at the process. We did not create accounts, enter medical information, or complete checkout, so this is what any visitor sees, not a patient's outcome.
- 1The plans page lists four terms per molecule — monthly, 3-month, 6-month and 12-month — each with both its monthly equivalent and the total charge, all before any intake
- 2A 5-minute assessment determines eligibility; a licensed U.S. provider reviews it in about 24 hours, and the site states you are only charged if prescribed
- 3If prescribed, medication ships in 2-3 days from a partner pharmacy with tracking; every plan states it includes injection supplies, shipping and unlimited provider messaging
What we noticed
- The month-to-month rate is now published for both molecules — $199 semaglutide, $299 tirzepatide — which closes the gap this record carried since August 2026
- The 6-month tier is an introductory rate, not a standing one: the plans page shows '$139/mo, SAVE $360' with no renewal figure, and the homepage footnote supplies the missing half — $1,194 per six months, or $199/mo, thereafter
- The FAQ names both pharmacy partners, the clinical group and its address, and states GLP-1s ship everywhere except Louisiana — a sentence that contradicts the 'nationwide' framing used elsewhere on the site
- The Terms of Service is Bask Health Inc's platform document, still carrying a testosterone-program membership section and three unfilled '[INSERT CUSTOMER SERVICE PHONE]' placeholders
Pricing
Prices re-verified
| Medication | Monthly | Plan |
|---|---|---|
| Compounded semaglutide | $199 | Injectable, month-to-monthThe standing no-commitment rate, shown on the plans page as 'MONTHLY PLAN … Billed monthly'. Every cheaper figure on that page buys a fixed term up front. |
| Compounded semaglutide | $149 | Injectable, 3-month planPay $447 every 3 months. Its 'SAVE $270' badge does not reconcile with anything the site publishes — against the $199 monthly plan the real 3-month saving is $150. |
| Compounded semaglutide | $139 → $199 | Injectable, 6-month plan$139/mo ($834) covers the FIRST six months only; the homepage footnote states it then renews at $1,194 per six months, i.e. $199/mo. The plans page shows the $139 and a 'SAVE $360' badge but never the renewal that badge is measured against. |
| Compounded semaglutide | $99 | Injectable, 12-month planPay $1,188 annually — the lowest advertised price on the site, and the longest commitment on it. |
| Oral semaglutide | $209 | Oral, 12-month planPrice for a 12-month supply purchase. A separate 6-month oral offer runs $199/mo for the first six months, then renews at $1,434 per six months, i.e. $239/mo. |
| Brand semaglutide | $1299 | Ozempic®, 12-month planPrice for a 12-month supply purchase. |
| Compounded tirzepatide | $299 | Injectable, month-to-monthThe standing no-commitment rate. This is the figure the August 2026 record recorded as unpublished; it is itemized on the plans page now, and it is $100 above semaglutide's. |
| Compounded tirzepatide | $209 | Injectable, 3-month planPay $627 every 3 months; its 'SAVE $270' badge does reconcile against the $299 monthly plan. |
| Compounded tirzepatide | $199 → $289 | Injectable, 6-month plan$199/mo ($1,194) covers the FIRST six months only; the homepage footnote states it then renews at $1,734 per six months, i.e. $289/mo — which the plans page does not show. |
| Compounded tirzepatide | $159 | Injectable, 12-month planPay $1,908 annually, in one charge. |
| Oral tirzepatide | $269 | Oral, 12-month planPrice for a 12-month supply purchase. |
| Brand tirzepatide | $1399 | Zepbound®, 12-month planPrice for a 12-month supply purchase. |
Swipe the table to see plan details →
HSA/FSA is usually accepted for GLP-1 telehealth — check your plan. Prices reflect what He and She MD disclosed publicly at our last review and change often; confirm the current number on He and She MD's site.
What we like
- A genuinely broad menu — compounded injectable, compounded oral, and FDA-approved brand (Ozempic, Zepbound) for both molecules, all priced on one platform
- Both month-to-month rates are published now ($199 semaglutide, $299 tirzepatide), so you can see what not committing actually costs — most of this roster shows only the prepay figure
- Names its pharmacies, its clinical group (Wasef Health PC) and its chief medical officer (Dr. Ozita Cooper, MD, dual board-certified in obesity medicine) — most of this roster names none of the three
- Every plan states it includes the medication, injection supplies, shipping and unlimited provider messaging, and that you are only charged if prescribed
- Same price at every dose, so titrating up never raises the bill
The caveats
- The 6-month tiers are introductory: semaglutide's $139/mo renews at $199/mo and tirzepatide's $199/mo at $289/mo, and the plans page shows the discount without the renewal
- The lowest advertised prices need 12 months paid up front — $1,188 for semaglutide, $1,908 for tirzepatide, in a single charge
- GLP-1s do not ship to Louisiana, which the FAQ states plainly and the rest of the site's 'nationwide' framing does not
- The Terms of Service bills 'approximately every 28-30 days' rather than monthly and makes membership fees non-refundable on cancellation, against a plans page badge reading 'No membership fees'
- One of the two named pharmacies, Jungle Jim's, is licensed in 44 states and by the site's own FAQ cannot dispense sterile compounds — injectable GLP-1s are sterile compounds, so an injectable order has to route through the other partner
He and She MD for moms: our verdict
$199/mo semaglutide, $299/mo tirzepatide month-to-month, dropping to $99 and $159 only on a full year prepaid. It names its pharmacies, its clinical group and its CMO. The advertised starting price is $139, but the regular rate settles nearer $199/mo — so read the headline as an intro offer, not as the monthly cost.
We looked at He and She MD the way moms actually have to: not just the monthly cost, but the right timing around pregnancy and nursing and honest, clear pricing from the start — the parts a generic weight-loss review skips.
What He and She MD actually costs
- Compounded semaglutide — Injectable, month-to-month: $199/mo
- Compounded semaglutide — Injectable, 3-month plan: $149/mo
- Compounded semaglutide — Injectable, 6-month plan: $139 to start, then $199/mo
- Compounded semaglutide — Injectable, 12-month plan: $99/mo
- Oral semaglutide — Oral, 12-month plan: $209/mo
- Brand-name semaglutide — Ozempic®, 12-month plan: $1299/mo
That's roughly in line with our list's median of ~$175/mo.
He and She MD prices flat across doses, so it doesn't climb as your dose does — which matters, because most women spend months titrating up.
That price covers the consult, the medication and shipping. It does not cover labs — that's billed separately.
The medications He and She MD prescribes
He and She MD prescribes semaglutide and tirzepatide — the two molecules with the strongest published weight-loss results, and having both on one account matters when insulin resistance (common with PCOS and after gestational diabetes) makes tirzepatide the better fit. It can point you toward FDA-approved brand-name pens as well as the compounded versions — approved products carry the manufacturer's own pregnancy and breastfeeding label, which is cleaner to hand to an OB-GYN.
There's a needle-free oral or sublingual option on the menu, which appeals to moms who have been putting off injections — just set your expectations: oral and buccal delivery of these peptides is far less studied than the injectable versions used in the trials.
Where it operates. He and She MD lists its coverage as: 49 states — everywhere except Louisiana.
Where He and She MD fits — and where it doesn't — for moms
A good fit if…
- you want a real clinician who reads your history with the right timing around pregnancy and nursing in mind, not a questionnaire that approves you automatically.
- you may need to switch between semaglutide and tirzepatide as your body and your hormones change.
Look elsewhere if…
- you want friction-free cancellation — the fine print here is where the complaints cluster.
Trust, safety and oversight
Our confidence in He and She MD's public data is high — the pricing, the pharmacies and the clinical network were all verifiable at our last review. As with any compounded GLP-1, the most useful thing moms can do is confirm which licensed pharmacy fills the prescription and what's in the formula — we explain how we score oversight in our scoring methodology.
A standing caution for moms: GLP-1 medications are not proven safe during pregnancy or breastfeeding, and every label advises against use. None of this changes that — plan the timing with your own healthcare provider.
The bottom line
He and She MD is a reasonable option — weigh it on the right timing around pregnancy and nursing and honest, clear pricing from the start against the alternatives below. For most moms, CoreAge Rx is still the best choice overall — see why it tops our ranking.
The bottom line
Best for: Moms who want brand-name and oral options alongside compounded on one platform, and who will either pay $199/mo month-to-month or prepay a year to reach $99.
Other gentle first steps
Providers we'd send a friend to, with the ones we work with listed first — CoreAge Rx leads our ranking on the score. Some of these links earn MamaGLP a referral commission.
- Meet CoreAge RxCoreAge RxOur #1 pick
$99/mo semaglutide, $149/mo tirzepatide, one flat price with both medications in a single account — and an intake that walks you through it instead of cornering you with a quiz.
- Meet ShedRx
$199/mo semaglutide, $299/mo tirzepatide month-to-month, with coaching, unlimited follow-ups and a full Spanish site in 49 states — and a two-month minimum you cannot cancel out of.
- Meet Synergy Rx
$199–299/mo semaglutide, $349–399/mo tirzepatide depending on form, plus brand options, all published on its products page with no consult required.
Keep comparing He and She MD
Head-to-heads and alternatives
Ranked boards
- Best GLP-1 for moms — a gentle first step
- Best GLP-1 for women — PCOS, cycles, perimenopause
- Best GLP-1 for first-timers (easiest to start)
- Most affordable GLP-1 with honest, clear pricing
- Best semaglutide for mothers — price and practicality
- Best semaglutide for women — compounded vs brand
- Best semaglutide for young moms — postpartum and budget
- Best tirzepatide for mothers — is it worth the extra
- Best tirzepatide for women — PCOS and insulin resistance
- Best GLP-1 with bilingual / Spanish-language support
He and She MD, answered
- How much does He and She MD cost?
- As of our last review, He and She MD's compounded pricing starts around $199/mo ($199/mo month-to-month, $99/mo on the 12-month plan semaglutide, $299/mo month-to-month, $159/mo on the 12-month plan tirzepatide). Confirm the current all-in price on He and She MD's site before you commit.
- Is He and She MD safe to use while breastfeeding?
- Here is the honest answer: no GLP-1 — compounded or brand-name — is established as safe during pregnancy or breastfeeding, and the labels advise against use; He and She MD is no exception. Plan any GLP-1 for after weaning, and talk the timing through with your own clinician.
- Does He and She MD offer both semaglutide and tirzepatide?
- Yes — He and She MD offers both. Tirzepatide's dual action is often preferred when insulin resistance is driving the weight, which matters with PCOS and after gestational diabetes.
- Where does He and She MD land in your ranking?
- He and She MD scores 60/100 on our Mama-Match Score (rank #111), which weights six things that matter to a first-timer. Our #1 pick, CoreAge Rx, leads the ranking — see how they compare.
Prices, states and verification reflect what He and She MD disclosed publicly at our last review; the Mama-Match Score is our editorial judgment under the published methodology. This is gentle background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See our medical disclaimer and how we're funded.