The best GLP-1 for women — judged on the questions we actually have.

1. #1

   Mama-Match

   Trimi Health

   Featured on this board

   Semaglutide $175/mo and tirzepatide $235/mo; no dose surcharge within your plan. Annual savings require prepayment and strict refund limits.

   Semaglutide:

   $175/mo

   Tirzepatide:

   $235/mo

   States:

   Advertises all 50 states; confirm your location

   Visit Trimi Health ↗Read the full review →
2. #2

   Mama-Match

   Gala Health

   $179/mo for either medication, flat across doses, with a genuinely gentle microdose tier — if you can live with an annual plan and a pharmacy it will not name.

   Semaglutide:

   $179/mo

   Tirzepatide:

   $179/mo

   States:

   All 50 states (as advertised)

   Visit Gala Health ↗Read the full review →
3. #3

   Mama-Match

   Sesame

   Brand only: Wegovy pill from about $149/mo, Zepbound about $349–$499/mo, with a real video visit — pricier and with more moving parts than a flat compounded plan, but transparent.

   Semaglutide:

   Brand only (Wegovy pill from ~$149/mo)

   Tirzepatide:

   Brand only (Zepbound ~$349–$499/mo)

   States:

   All 50 states

   Visit Sesame ↗Read the full review →
4. #4

   Mama-Match

   Enhance MD

   $249/mo semaglutide, $329/mo tirzepatide with no commitment ($212 and $280 on the 12-month plan), a named Medical Director and a real video visit before anything is prescribed.

   Semaglutide:

   $249/mo with no commitment ($212/mo on the 12-month plan)

   Tirzepatide:

   $329/mo with no commitment ($280/mo on the 12-month plan)

   States:

   40 states + DC (not AL, AR, GA, HI, LA, MS, MO, ND, SC, TN)

   Visit Enhance MD ↗Read the full review →
5. #5

   Mama-Match

   Found Health

   $299/mo month-to-month for either molecule ($169 on the 12-month prepay), flat across doses, insurance accepted in 49 states, brand access — plus a separate membership fee.

   Semaglutide:

   $299/mo month-to-month ($169/mo on the 12-month prepay)

   Tirzepatide:

   $299/mo month-to-month ($169/mo on the 12-month prepay)

   States:

   Not disclosed — no published state list

   Visit Found Health ↗Read the full review →
6. #6

   Mama-Match

   Willow

   $299/mo semaglutide, $399/mo tirzepatide, both public before any questionnaire, with a name and a face on every prescribing doctor — 36 states only, and the cost climbs with your dose.

   Semaglutide:

   $299/mo

   Tirzepatide:

   $399/mo

   States:

   36 states (not AL, AK, AR, DE, KS, LA, MS, ND, NM, RI, SD, UT, VT, WV)

   Visit Willow ↗Read the full review →
7. #7

   Mama-Match

   Luvo Health

   $249/mo semaglutide (tablets $279), $339/mo tirzepatide, microdose $179 — every price public before any intake. It never names the pharmacy that compounds it.

   Semaglutide:

   $249/mo

   Tirzepatide:

   $339/mo

   States:

   50 states (as advertised)

   Visit Luvo Health ↗Read the full review →
8. #8

   Mama-Match

   ShedRx

   $199/mo semaglutide, $299/mo tirzepatide month-to-month, with coaching, unlimited follow-ups and a full Spanish site in 49 states — and a two-month minimum you cannot cancel out of.

   Semaglutide:

   $199/mo (month-to-month)

   Tirzepatide:

   $299/mo (month-to-month)

   States:

   All 50 states (not Puerto Rico)

   Visit ShedRx ↗Read the full review →
9. #9

   Mama-Match

   yourEra

   From $99/mo semaglutide, $169/mo tirzepatide, physician-founded with cancel-anytime terms — the rates are a floor that only firms up after the eligibility check.

   Semaglutide:

   From $99/mo (starting rate)

   Tirzepatide:

   From $169/mo (starting rate)

   States:

   U.S. (availability varies by state)

   Visit yourEra ↗Read the full review →
10. #10

    Mama-Match

    Oak

    From $119/mo semaglutide, $185/mo tirzepatide, fully asynchronous with free delivery — the real monthly price and the cancellation terms only appear after you sign up.

    Semaglutide:

    From $119/mo (starting rate)

    Tirzepatide:

    From $185/mo (starting rate)

    States:

    ~45 states (as reported; list not published)

    Visit Oak ↗Read the full review →

GLP-1 and women's health, answered

Do GLP-1 medications help with PCOS and insulin resistance?

PCOS requires a clinical discussion, not a provider ranking. Ask what evidence supports the exact treatment being considered, how your other medicines and pregnancy plans affect it, and whether you need specialist follow-up. Appearing on this list does not verify that a program offers specialist PCOS care.

Can I take a GLP-1 while I'm on hormonal birth control?

Ask your prescriber, because the answer depends on the medication. Tirzepatide's labeling advises women using oral contraceptives to switch to a non-oral method, or add a barrier method, for four weeks after starting and after each dose increase — because these medicines slow stomach emptying, which can affect how a pill is absorbed. Semaglutide's labeling does not carry that same instruction. Either way, tell the clinician exactly what you use.

Will a GLP-1 change my period?

Possibly, and we would rather be honest that this is under-studied. Cycle changes are not a listed side effect, but weight loss and improved insulin sensitivity can shift cycles on their own — women with PCOS in particular sometimes find that ovulation returns and periods become more regular. That is worth knowing for a second reason: a cycle that becomes predictable again can mean fertility returns sooner than expected.

What if I'm trying to get pregnant, or might be?

Pregnancy and breastfeeding need separate discussions with your clinician. GLP-1 weight-loss treatment is not recommended during pregnancy. During breastfeeding, the exact drug and formulation matter: Wegovy tablets are not recommended because of the SNAC absorption ingredient. Injectable semaglutide and tirzepatide labels call for weighing benefits, risks and the limits of infant-safety data; they do not establish that treatment is safe for every nursing parent. Compounded products do not inherit FDA approval from the branded drug. Discuss your own medication and timing before starting or changing treatment.

Does a GLP-1 work differently in perimenopause?

There is no good evidence that it works less well, and no good evidence that it is a treatment for menopausal weight change either — that research simply has not been done at the size it deserves. What we do know is that shifting hormones, sleep and muscle loss all affect this decade, so protecting muscle with protein and strength work matters more, not less. A clinician who knows where you are in that transition is worth more than any ranking.

Rankings reflect our published methodology. This page is informational and is not medical advice; compounded medications are not FDA-approved brand-name products. See our medical disclaimer.