Mama-Match
Rx.com review
Semaglutide $175/mo with no commitment; the advertised $146 is $875 prepaid for six months. Nothing renews on its own.
- HSA / FSA eligible
- Independently scored
- No insurance needed
Every medical claim is cited to its primary source — the clinical trial or the FDA label — so you can open it and check it yourself. No one on this team is your healthcare professional. What follows is friendly information, never medical advice.
Gentler first steps than Rx.com
Providers we'd send a friend to, with the ones we work with listed first — CoreAge Rx leads our ranking on the score. Some of these links earn MamaGLP a referral commission.
- Meet CoreAge RxCoreAge RxOur #1 pick
$99/mo semaglutide, $149/mo tirzepatide, one flat price with both medications in a single account — and an intake that walks you through it instead of cornering you with a quiz.
- Meet Oak
From $119/mo semaglutide, $185/mo tirzepatide, fully asynchronous with free delivery — the real monthly price and the cancellation terms only appear after you sign up.
- Meet Direct Meds
$249/mo semaglutide, $299/mo tirzepatide, injection or sublingual — with a 2025 FDA warning letter and a run of BBB complaints about surprise 3-month charges.
Rx.com at a glance
- Semaglutide
- $175/mo
- Tirzepatide
- $285/mo
- Coverage
- 49 states — all but Alaska, per its own FAQ
- Brand-name
- Compounded only
How we scored Rx.com
Each factor is judged from Rx.com's actual pricing, disclosures and support, then combined into the Mama-Match Score of 78/100 using the same weighted six-factor framework we apply to every provider — never influenced by whether a provider pays us.
A reasonable intake, though a little more standard than hand-held.
The cost is unpredictable, hidden behind a quiz, or in the premium range.
Little public detail about who oversees your care, and how.
Wide coverage, though not confirmed in every state.
Standard support — enough to keep your rhythm, but not personalized.
Cancellation is manageable but not frictionless.
How we verified this review
- Last reviewed
- September 2026
- Confidence
- High
- Primary source
- rx.com
$175 and $285 month to month, the same price at any dose, with the visit, syringes and cold shipping inside. The advertised $146 is the six-month plan: $875 in one go. Nothing renews on its own. And it is 49 states, not 50 — Alaska is out.
Pricing
Prices re-verified
| Medication | Monthly | Plan |
|---|---|---|
| Compounded semaglutide | $175 | Any dose, month to monthThe one-month plan, no commitment: $175 in a single payment. It is the figure you can pay month to month without putting anything up front. |
| Compounded semaglutide | $165 | Any dose, 3-month plan$495 in one go. Not a monthly price: a prepayment for three months. |
| Compounded semaglutide | $146 | Any dose, 6-month plan⛔ THIS IS THE ADVERTISED $146. It is $875 in one payment for six months, not $146 a month. The homepage calls it an “Exclusive Lifetime Offer” without saying on the same line that you prepay the half-year. |
| Compounded tirzepatide | $285 | Any dose, month to monthThe one-month plan: $285 in a single payment. |
| Compounded tirzepatide | $265 | Any dose, 3-month plan$795 in one go. |
| Compounded tirzepatide | $259 | Any dose, 6-month plan$1,550 in one go. The $259 that shows up in comparisons comes from here. |
Swipe the table to see plan details →
HSA/FSA is usually accepted for GLP-1 telehealth — check your plan. Prices reflect what Rx.com disclosed publicly at our last review and change often; confirm the current number on Rx.com's site.
What we like
- The entire price table is published before any intake
- The same price at any dose, with the milligram range published
- Nothing renews on its own: they ask you before every refill
- The visit, the syringes, the cold shipping and the messaging are inside the price
- It says which state is excluded instead of promising all fifty
The caveats
- The advertised $146 is the six-month plan, $875 in one payment
- The homepage badge promises all 50 states and its own FAQ says 49
- Alaska is excluded, and some states require a video visit
- Medication cannot be returned once shipped
- Nothing about postpartum, or how long to wait after giving birth
Rx.com for moms: our verdict
Semaglutide $175/mo with no commitment; the advertised $146 is $875 prepaid for six months. Nothing renews on its own. It runs about $175/mo, flat across every dose.
We looked at Rx.com the way moms actually have to: not just the monthly cost, but the right timing around pregnancy and nursing and honest, clear pricing from the start — the parts a generic weight-loss review skips.
What Rx.com actually costs
- Compounded semaglutide — Any dose, month to month: $175/mo
- Compounded semaglutide — Any dose, 3-month plan: $165/mo
- Compounded semaglutide — Any dose, 6-month plan: $146/mo
- Compounded tirzepatide — Any dose, month to month: $285/mo
- Compounded tirzepatide — Any dose, 3-month plan: $265/mo
- Compounded tirzepatide — Any dose, 6-month plan: $259/mo
That's roughly in line with our list's median of ~$175/mo.
Rx.com prices flat across doses, so it doesn't climb as your dose does — which matters, because most women spend months titrating up.
That price covers the consult, the medication, shipping and coaching.
The medications Rx.com prescribes
Rx.com prescribes semaglutide and tirzepatide — the two molecules with the strongest published weight-loss results, and having both on one account matters when insulin resistance (common with PCOS and after gestational diabetes) makes tirzepatide the better fit. These are compounded formulas from a licensed pharmacy — the reason the price stays low — but compounded GLP-1s are not FDA-approved finished products the way Wegovy and Zepbound are.
Where it operates. Rx.com lists its coverage as: 49 states — all but Alaska, per its own FAQ.
Where Rx.com fits — and where it doesn't — for moms
A good fit if…
- the monthly cost is a real barrier and you want a low, predictable number.
- you may need to switch between semaglutide and tirzepatide as your body and your hormones change.
Look elsewhere if…
- you specifically want an FDA-approved brand-name pen with its own pregnancy and breastfeeding label.
- you'd rather have a clinician talk the timing through with you, with the right timing around pregnancy and nursing in mind — that's what our #1 pick, CoreAge Rx, is built for.
Trust, safety and oversight
Our confidence in Rx.com's public data is high — the pricing, the pharmacies and the clinical network were all verifiable at our last review. As with any compounded GLP-1, the most useful thing moms can do is confirm which licensed pharmacy fills the prescription and what's in the formula — we explain how we score oversight in our scoring methodology.
A standing caution for moms: GLP-1 medications are not proven safe during pregnancy or breastfeeding, and every label advises against use. None of this changes that — plan the timing with your own healthcare provider.
The bottom line
Rx.com is a reasonable option — weigh it on the right timing around pregnancy and nursing and honest, clear pricing from the start against the alternatives below. For most moms, CoreAge Rx is still the best choice overall — see why it tops our ranking.
The bottom line
Best for: A mom who wants the full price table before she gives out a single detail, and who cares more about never being auto-charged than about the lowest figure.
Keep comparing Rx.com
Head-to-heads and alternatives
Ranked boards
- Best GLP-1 for moms — a gentle first step
- Best GLP-1 for women — PCOS, cycles, perimenopause
- Best GLP-1 for first-timers (easiest to start)
- Most affordable GLP-1 with honest, clear pricing
- Best semaglutide for mothers — price and practicality
- Best semaglutide for women — compounded vs brand
- Best semaglutide for young moms — postpartum and budget
- Best tirzepatide for mothers — is it worth the extra
- Best tirzepatide for women — PCOS and insulin resistance
- Best GLP-1 with bilingual / Spanish-language support
Rx.com, answered
- Is it really $146 a month?
- Only if you prepay half a year. The $146 is the six-month plan, billed as $875 in a single payment. If you want to pay month to month, semaglutide is $175 and you can stop whenever you like. The advertised figure is real, but it is an $875 decision, not a monthly one.
- Will I get charged automatically every month?
- No, and it is one of the few that says so this plainly. Its own page states that the plan does not renew automatically and that nothing ships or is charged until you confirm with the care team before each refill. Canceling costs nothing. The only thing with no way back is medication already shipped.
- Does the price go up when my dose does?
- No. It is the same price from 0.25 to 2.4 mg on semaglutide and from 2.5 to 15 mg on tirzepatide, and they say so outright. That matters most at the start, because the dose almost always climbs over the first months and elsewhere the bill climbs with it.
- Is this okay if I'm pregnant or nursing?
- No. Its own safety information excludes pregnancy, breastfeeding and anyone trying to conceive, and the same is true of every GLP-1 we cover. If you are in any of those three situations, this is not the conversation: the conversation is with your OB or your pediatrician first.
Prices, states and verification reflect what Rx.com disclosed publicly at our last review; the Mama-Match Score is our editorial judgment under the published methodology. This is gentle background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See our medical disclaimer and how we're funded.