Head to head for first-timers
CoreAge Rx vs Sesame
CoreAge Rx and Sesame both offer GLP-1 telehealth, but they make different trade-offs on how gentle the start is, honest pricing, real support and access. Here they are side by side on the Mama-Match Score — our first-timer rubric.
CoreAge Rx
Higher scoreRank #1 for first-timers · Grade A
Mama-Match
Best for: Moms who want a clear, honest first step — a real clinician instead of a questionnaire, a flat price, and the freedom to pause when life needs you to.
Visit CoreAge RxSesame
Rank #7 for first-timers · Grade B
Mama-Match
Best for: Moms who'd rather have FDA-approved brand-name medication and a real clinical visit than the lowest compounded price, and who don't mind separate subscription and medication bills.
Visit SesameThe verdict for a first step
CoreAge Rx edges out Sesame on the Mama-Match Score, 94 to 83 (A vs B). Moms who want a clear, honest first step — a real clinician instead of a questionnaire, a flat price, and the freedom to pause when life needs you to.
Sesame is still a genuine option — brand only: Wegovy pill from about $149/mo, Zepbound about $349–$499/mo, with a real video visit — pricier and with more moving parts than a flat compounded plan, but transparent. Weigh the six first-timer factors below against your own priorities.
Side by side on all six factors
Both providers judged on the same first-timer rubric — the higher side on each factor is marked. See the methodology.
Price, access and features
| Detail | CoreAge Rx | Sesame |
|---|---|---|
| Mama-Match Score | 94/100 · A | 83/100 · B |
| Overall rank | #1 | #7 |
| Semaglutide | $99/mo | Brand only (Wegovy pill from ~$149/mo) |
| Tirzepatide | $149/mo | Brand only (Zepbound ~$349–$499/mo) |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Mama-Match
CoreAge Rx
Rank #1 · Grade A
What we like
- One flat monthly price, with no teaser rate that jumps after the first month — you know the number before you commit
- A clinician reads your history and will genuinely talk timing with you if you're postpartum, breastfeeding, or trying to conceive
- Semaglutide and tirzepatide in one account, so you and a clinician can choose — and switch — without starting over
The caveats
- Not the rock-bottom teaser price — a couple of marketplaces dangle a lower first-month number
- Compounded medication only, not FDA-approved brand-name Ozempic or Wegovy
- A general metabolic program, not a dedicated OB-GYN or hormone consult
Mama-Match
Sesame
Rank #7 · Grade B
What we like
- A real video visit with a licensed clinician, plus labs and messaging in the subscription
- FDA-approved brand-name options (Wegovy pill, Ozempic, Zepbound) with the manufacturer's own label
- Transparent cash-pay marketplace pricing — no insurance needed, HSA/FSA commonly accepted
The caveats
- No longer offers low-cost compounded GLP-1s — it exited that market in 2025
- The subscription and the medication are billed separately, so the true monthly cost is higher than the headline
- Brand-name medication runs $149–$499/mo, well above the flat compounded programs
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Mama-Match Score. Prices, states and verification reflect what each provider disclosed publicly at our last review; the Mama-Match Score is our editorial judgment under the methodology. Prices change — confirm them on each provider’s site. Not medical advice; see our disclosure.
More head-to-heads
Keep comparing CoreAge Rx and Sesame with the other providers we review for women.
- CoreAge Rx vs Eden
- CoreAge Rx vs Pallas Health
- CoreAge Rx vs Trimi Health
- Sesame vs Synergy Rx
- Sesame vs Form Health
- Sesame vs Hers
Or browse the full comparison hub.