Head to head for first-timers
Hers vs Sesame
Hers and Sesame both offer GLP-1 telehealth, but they make different trade-offs on how gentle the start is, honest pricing, real support and access. Here they are side by side on the Mama-Match Score — our first-timer rubric.
Hers
Rank #9 for first-timers · Grade B−
Mama-Match
Best for: Someone seeking branded medication and app-based support who accepts a separate subscription for care.
Visit HersSesame
Higher scoreRank #4 for first-timers · Grade B
Mama-Match
Best for: Moms who'd rather have FDA-approved brand-name medication and a real clinical visit than the lowest compounded price, and who don't mind separate subscription and medication bills.
Visit SesameThe verdict for a first step
Sesame edges out Hers on the Mama-Match Score, 83 to 81 (B vs B−). Moms who'd rather have FDA-approved brand-name medication and a real clinical visit than the lowest compounded price, and who don't mind separate subscription and medication bills.
Hers is still a genuine option — hers offers branded GLP-1s with messaging follow-up; the real bill combines medication and a required membership. Its company received FDA warning letter #716825 in September 2025. Weigh the six first-timer factors below against your own priorities.
Side by side on all six factors
Both providers judged on the same first-timer rubric — the higher side on each factor is marked. See the methodology.
Price, access and features
| Detail | Hers | Sesame |
|---|---|---|
| Mama-Match Score | 81/100 · B− | 83/100 · B |
| Overall rank | #9 | #4 |
| Semaglutide | From $298/mo with oral Wegovy; $348/mo with the pen, including membership | Brand only (Wegovy pill from ~$149/mo) |
| Tirzepatide | From $448/mo with Zepbound, including membership | Brand only (Zepbound ~$349–$499/mo) |
| Coverage | Availability varies by state; not available in all 50 states | All 50 states |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Yes | Yes |
Mama-Match
Hers
Rank #9 · Grade B−
What we like
- Offers Wegovy tablets and pens, and Zepbound vials or KwikPen
- Membership includes messaging access to licensed providers and monthly follow-ups
- The membership page separates the cost of care from medication
The caveats
- FDA warning letter #716825, dated September 9, 2025, to Hims & Hers Health, Inc. dba Hers
- Membership renews at $149/month after the $39 first month and does not guarantee a prescription
- Canceling the medication plan alone does not cancel membership
Mama-Match
Sesame
Rank #4 · Grade B
What we like
- A real video visit with a licensed clinician, plus labs and messaging in the subscription
- FDA-approved brand-name options (Wegovy pill, Ozempic, Zepbound) with the manufacturer's own label
- Transparent cash-pay marketplace pricing — no insurance needed, HSA/FSA commonly accepted
The caveats
- No longer offers low-cost compounded GLP-1s — it exited that market in 2025
- The subscription and the medication are billed separately, so the true monthly cost is higher than the headline
- Brand-name medication runs $149–$499/mo, well above the flat compounded programs
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Mama-Match Score. Prices, states and verification reflect what each provider disclosed publicly at our last review; the Mama-Match Score is our editorial judgment under the methodology. Prices change — confirm them on each provider’s site. Not medical advice; see our disclosure.
More head-to-heads
Keep comparing Hers and Sesame with the other providers we review for women.
- Hers vs Noom Med
- Hers vs CoreAge Rx
- Hers vs Eden
- Sesame vs Form Health
- Sesame vs Synergy Rx
- Sesame vs CoreAge Rx
Or browse the full comparison hub.