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Head-to-head for first-timers

Hers vs Sesame

Hers and Sesame both offer GLP-1 telehealth, but they make different trade-offs on how gentle the start is, honest pricing, real support and access. Here they are side-by-side on the Mama-Match Score — our first-timer rubric.

Hers

Higher score

Ranked #3 for first-timers · Grade B+

Mama-Match

Best for: Moms who want a familiar, women-first brand and the smoothest possible signup.

Visit Hers
vs

Sesame

Ranked #9 for first-timers · Grade B

Mama-Match

Best for: Confident, budget-first moms who are comfortable steering their own care.

Visit Sesame

The verdict for a first step

Higher Mama-Match Score: Hers

Hers edges out Sesame on the Mama-Match Score, 87 to 83 (B+ vs B). Moms who want a familiar, women-first brand and the smoothest possible signup.

Sesame is still a genuine option — a cash-pay medical marketplace with some of the lowest posted GLP-1 prices anywhere — you're booking a clinician yourself, which is cheap and flexible but less hand-held. Weigh the six first-timer factors below against your own priorities.

Side-by-side on the six factors

Both providers scored on the same first-timer rubric — the higher side on each factor is marked. See the methodology.

Hers Sesame
Gentle, easy start9179
Hers
Sesame
Honest, upfront pricing8492
Hers
Sesame
Real clinician support8378
Hers
Sesame
Available nationwide9188
Hers
Sesame
Ongoing help & check-ins8474
Hers
Sesame
Simple, fair cancellation8585
Hers
Sesame

Price, access & features

DetailHersSesame
Mama-Match Score87/100 · B+83/100 · B
Overall rank#3#9
Semaglutide$199/mo$99/mo
TirzepatideNot disclosed$199/mo
CoverageAll 50 statesAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only

Mama-Match

Hers

Ranked #3 · Grade B+

What we like

  • Explicit women-focused brand many moms already recognize and trust
  • Nationwide, with a very smooth app-driven signup and an oral/sublingual option
  • Simple, mass-market onboarding that doesn't assume any background

The caveats

  • Tirzepatide pricing isn't consistently posted up front
  • Lighter on labs and metabolic detail behind the polished branding

Mama-Match

Sesame

Ranked #9 · Grade B

What we like

  • Among the lowest posted cash prices for compounded semaglutide
  • Transparent, upfront marketplace pricing — no membership to decode
  • Nationwide, with flexible clinician booking on your schedule

The caveats

  • You drive the process — less of a warm, guided first-timer experience
  • Care can feel piecemeal since it's a marketplace, not one continuous program

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Mama-Match Score. Pricing, states and verification reflect each provider's public disclosures at last review; the Mama-Match Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

More head-to-heads

Keep comparing Hers and Sesame against other providers we review for women.

Or browse the full comparison hub.