Head to head for first-timers
Hers vs Sesame
Hers and Sesame both offer GLP-1 telehealth, but they make different trade-offs on how gentle the start is, honest pricing, real support and access. Here they are side by side on the Mama-Match Score — our first-timer rubric.
Hers
Rank #13 for first-timers · Grade B−
Mama-Match
Best for: Moms who want a familiar, women-focused brand and are comfortable budgeting for a separate membership on top of the posted medication price.
Visit HersSesame
Higher scoreRank #7 for first-timers · Grade B
Mama-Match
Best for: Moms who'd rather have FDA-approved brand-name medication and a real clinical visit than the lowest compounded price, and who don't mind separate subscription and medication bills.
Visit SesameThe verdict for a first step
Sesame edges out Hers on the Mama-Match Score, 83 to 82 (B vs B−). Moms who'd rather have FDA-approved brand-name medication and a real clinical visit than the lowest compounded price, and who don't mind separate subscription and medication bills.
Hers is still a genuine option — ⛔ Its company carries an FDA warning letter (#716825, Sept. 2025). It sells FDA-approved brand, but the posted price leaves out a $149/mo membership. Weigh the six first-timer factors below against your own priorities.
Side by side on all six factors
Both providers judged on the same first-timer rubric — the higher side on each factor is marked. See the methodology.
Price, access and features
| Detail | Hers | Sesame |
|---|---|---|
| Mama-Match Score | 82/100 · B− | 83/100 · B |
| Overall rank | #13 | #7 |
| Semaglutide | $298/mo all-in (medication + membership) | Brand only (Wegovy pill from ~$149/mo) |
| Tirzepatide | $448/mo all-in (medication + membership) | Brand only (Zepbound ~$349–$499/mo) |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Yes | Yes |
Mama-Match
Hers
Rank #13 · Grade B−
What we like
- Now sells FDA-approved brand medication (Wegovy, Zepbound) instead of compounded semaglutide
- An explicitly women-focused brand that many moms already recognize and trust
- Nationwide, with a very smooth app-guided signup and an oral/sublingual option
The caveats
- ⛔ FDA warning letter #716825, dated September 9, 2025, to Hims & Hers Health, Inc. dba Hers — its sister brand, Hims, got its own the same day (#716567)
- The 'from $149/mo' price is medication only — a separate $149/mo membership (billed apart, $39 the first month) nearly doubles the real ongoing cost
- Less emphasis on labs and metabolic detail behind the polished brand
Mama-Match
Sesame
Rank #7 · Grade B
What we like
- A real video visit with a licensed clinician, plus labs and messaging in the subscription
- FDA-approved brand-name options (Wegovy pill, Ozempic, Zepbound) with the manufacturer's own label
- Transparent cash-pay marketplace pricing — no insurance needed, HSA/FSA commonly accepted
The caveats
- No longer offers low-cost compounded GLP-1s — it exited that market in 2025
- The subscription and the medication are billed separately, so the true monthly cost is higher than the headline
- Brand-name medication runs $149–$499/mo, well above the flat compounded programs
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Mama-Match Score. Prices, states and verification reflect what each provider disclosed publicly at our last review; the Mama-Match Score is our editorial judgment under the methodology. Prices change — confirm them on each provider’s site. Not medical advice; see our disclosure.
More head-to-heads
Keep comparing Hers and Sesame with the other providers we review for women.
- Hers vs CoreAge Rx
- Hers vs Eden
- Hers vs Noom Med
- Sesame vs CoreAge Rx
- Sesame vs Synergy Rx
- Sesame vs Form Health
Or browse the full comparison hub.