Head-to-head for first-timers
Sesame vs Zealthy
Sesame and Zealthy both offer GLP-1 telehealth, but they make different trade-offs on how gentle the start is, honest pricing, real support and access. Here they are side-by-side on the Mama-Match Score — our first-timer rubric.
Sesame
Ranked #9 for first-timers · Grade B
Mama-Match
Best for: Confident, budget-first moms who are comfortable steering their own care.
Visit SesameZealthy
Higher scoreRanked #8 for first-timers · Grade B
Mama-Match
Best for: Moms watching the budget who still want clear, posted pricing on both medicines.
Visit ZealthyThe verdict for a first step
Zealthy edges out Sesame on the Mama-Match Score, 84 to 83 (B vs B). Moms watching the budget who still want clear, posted pricing on both medicines.
Sesame is still a genuine option — a cash-pay medical marketplace with some of the lowest posted GLP-1 prices anywhere — you're booking a clinician yourself, which is cheap and flexible but less hand-held. Weigh the six first-timer factors below against your own priorities.
Side-by-side on the six factors
Both providers scored on the same first-timer rubric — the higher side on each factor is marked. See the methodology.
Price, access & features
| Detail | Sesame | Zealthy |
|---|---|---|
| Mama-Match Score | 83/100 · B | 84/100 · B |
| Overall rank | #9 | #8 |
| Semaglutide | $99/mo | $135/mo |
| Tirzepatide | $199/mo | $225/mo |
| Coverage | All 50 states | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Mama-Match
Sesame
Ranked #9 · Grade B
What we like
- Among the lowest posted cash prices for compounded semaglutide
- Transparent, upfront marketplace pricing — no membership to decode
- Nationwide, with flexible clinician booking on your schedule
The caveats
- You drive the process — less of a warm, guided first-timer experience
- Care can feel piecemeal since it's a marketplace, not one continuous program
Mama-Match
Zealthy
Ranked #8 · Grade B
What we like
- Low, posted monthly pricing on both semaglutide and tirzepatide
- Nationwide coverage with a quick, low-friction signup
- Straightforward compounded model — you see the cost before committing
The caveats
- Leaner on ongoing coaching and hand-holding than the premium programs
- Compounded only, with no brand-name route
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes a Mama-Match Score. Pricing, states and verification reflect each provider's public disclosures at last review; the Mama-Match Score is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.
More head-to-heads
Keep comparing Sesame and Zealthy against other providers we review for women.
- Sesame vs CoreAge Rx
- Sesame vs Eden
- Sesame vs Hers
- Zealthy vs Form Health
- Zealthy vs Noom Med
- Zealthy vs Trimi Health
Or browse the full comparison hub.